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Who Can Prescribe Antidepressants?

Daniel Z. Lieberman, MD

Reviewed by Daniel Z. Lieberman, MD

Written by Sian Ferguson

Published 04/22/2022

Updated 11/19/2025

Key Takeaways:

  • Antidepressants must be prescribed by a licensed healthcare provider — a primary care physician (PCP), psychiatrist, or nurse practitioner.

  • You can start with your PCP or an online provider through a telehealth platform like Hers.

  • Therapists, counselors, and psychologists (in most states) can’t prescribe medication but can offer talk therapy and emotional support.

  • Depression is treatable. A conversation with a provider is a strong first step toward feeling better.


When you’re dealing with depression, everyday tasks can feel so overwhelming to the point of being debilitating. Fortunately, there are treatment options — one of them being antidepressants.

Antidepressants can be very effective, which is why they’re often considered a first-line treatment. They work by targeting neurotransmitters in your brain to help regulate your mood and how you respond to stress.

But how exactly do you get antidepressants? Who can prescribe antidepressants? This type of medication has to be prescribed by a licensed healthcare provider — but not just any healthcare provider. We’ll walk you through who to talk to and what to expect.

Who Can Prescribe Antidepressants?

To get antidepressants, you’ll first need a prescription. Primary care providers (PCPs), nurse practitioners, and psychiatrists are all qualified to prescribe antidepressant medications.

We’ll dig into the differences below.

Primary Care Providers

Seeing a primary care provider — also called a primary care doctor or primary care physician — is an excellent first step in getting antidepressants. 

The benefit of using your own PCP is that you have an established relationship with them. They’ll already have your medical history on record, and since you’ve seen them before, it might be easier to approach them with this topic.

Nurse Practitioners

Psychiatric nurse practitioners (often called psychiatric-mental health nurse practitioners, or PMHNPs) are advanced-practice registered nurses with specialized training in mental health.

A psychiatric nurse practitioner or general nurse practitioner can evaluate, diagnose, and treat mental health conditions like depression and anxiety. And, yes, they can prescribe antidepressants in most states.

Depending on your state, you might see a PMHNP in a private practice, clinic, or online through a telehealth platform.

Just like other prescribers, psychiatric nurse practitioners will assess your symptoms, medical history, and overall well-being before determining if an antidepressant is appropriate for you.

Psychiatrists

A psychiatrist is a medical doctor (MD) who specializes in treating mental health disorders, like:

  • Depression

  • Panic disorder

  • Bipolar disorder

  • Anxiety

  • Obsessive-compulsive disorder (OCD)

They have extensive knowledge in their field and can use their deep expertise to create a plan tailored to your needs.

Psychiatrists can provide prescription medications and offer psychotherapy treatments, like cognitive behavioral therapy (CBT).

Read: How to Find a Therapist: A Step-by-Step Guide

Antidepressants are complex medications (some with more troublesome side effects than others), so it’s a good thing that not just anyone can prescribe them.

Though they can offer great mental health services, here are a few people who can’t prescribe antidepressants:

With that being said, these providers can still offer mental health care in the form of talk therapy. Talk therapy can be used with or without mental health medication — in fact, both medication and talk therapy might be a part of your depression treatment plan.

Again, your best bet for getting antidepressants is to connect with your primary care provider or find a psychiatrist.

Related: Psychologist vs. Psychiatrist for Depression

Deciding on a healthcare provider might seem hard, but it doesn’t have to be. The most important thing is that you talk to someone you feel like you can trust and be transparent with about your symptoms.

Here are a few questions to consider in the search for a provider:

  • Have you been treated for mental health before?

  • How severe are your mental health symptoms?

  • Do you definitely want to take antidepressants, or are you undecided?

  • How soon do you want to start taking antidepressants?

Ultimately, do what feels right for you, and know that you can always change course if needed.

Talking about your mental health can feel intimidating, especially when you’re not sure how to start.

Here are a few practical tips to help you bring up antidepressants with your provider — whether that’s your primary care provider, a psychiatrist, or a licensed provider through an online platform like Hers.

1. Be Honest About Your Symptoms

You can bring up antidepressants by simply explaining that you’re feeling depressed and saying you’d like some help.

Try to describe what you’ve been feeling as clearly as possible — even if it’s uncomfortable. Mention how long you’ve felt this way and how it’s impacting your daily life.

For example, you might say, “I’ve been feeling really down and unmotivated for a few months now, and it’s starting to affect my work and relationships. I’m interested in exploring antidepressant medication.”

2. Ask About All Your Options

Your provider may suggest antidepressants, therapy, or lifestyle changes — often a combination of these works best.

You could ask:

  • What medication options are there?

  • Which medication is the most appropriate for what I’m experiencing?

  • Are there any lifestyle changes that could help me feel better?

  • Do you recommend talk therapy? If so, can you give me a referral?

If you’re uncomfortable with the treatment plan your provider suggests, don’t be afraid to ask if there are other options.

3. Take Notes or Bring Questions

Writing things down ahead of time can help you feel more prepared — and ensure you don’t forget anything during your appointment.

You might find these questions helpful:

  • How long will it take before I feel a difference on this medication?

  • How long will I need to take an antidepressant?

  • What side effects can I expect?

If you’re not sure about starting medication, that’s okay. Your provider can help you understand the benefits, potential side effects, and what to expect.

Remember, there’s no “right” way to ask for help — what matters is that you start the conversation. Whether you meet with your provider in person or online, you deserve care that makes you feel heard, supported, and hopeful.

Whether your appointment is online or in person, your healthcare provider will likely start the conversation by asking about your symptoms and lifestyle habits, like sleep, smoking, and drinking.

Your provider might ask if you’ve experienced these common symptoms and signs of depression:

  • Pessimistic, despondent feelings

  • A sad, anxious, or “empty” mood

  • Fatigue and lower energy levels

  • Slow speech or movement

  • Difficulty sleeping or oversleeping

  • Trouble focusing, making decisions, or remembering things

  • Loss of interest in hobbies or activities you once enjoyed

  • Physical aches and pains

  • Irritability and annoyance

  • Weight gain or weight loss 

  • Thoughts of death or suicidal thoughts and behaviors

Knowing your symptoms can help your provider figure out whether you’re experiencing depression or other mental health conditions — for example, an anxiety disorder. Some people experience more than one.

Depending on your symptoms, lifestyle, and other factors, your healthcare provider will come up with a treatment plan.

There are multiple types of antidepressants available.

Some of the most commonly used antidepressants include:

  • Selective serotonin reuptake inhibitors (SSRIs)

  • Serotonin-norepinephrine reuptake inhibitors (SNRIs)

  • Monoamine oxidase inhibitors (MAOIs)

  • Tricyclic antidepressants (TCAs)

  • Atypical antidepressants

Your provider might also suggest talk therapy, which can be really helpful for managing your mental health. While psychiatrists can provide talk therapy, they might refer you to a therapist for more specialized care.

The important thing to remember is that there’s no one-size-fits-all treatment when it comes to depression. If your medication doesn’t work for you, or if the side effects are unbearable, you can schedule a follow-up consultation with your provider.

If you feel like depression is interfering with your life, don’t wait until it gets worse before seeking help. With guidance from a healthcare professional, you can come up with a treatment plan best suited for your needs.

If you start to feel overwhelmed, remember: 

  • There’s nothing wrong with needing mental health medication. Just as you may need medication when you have the flu or when you break a bone, you might need meds when your mental health is struggling. There’s no shame in getting the treatment you need.

  • Talk about it. Whether it’s reaching out to a loved one, exploring psychotherapy, or joining anonymous support groups, opening up can make you feel less alone. And if you don’t want to leave your home, online therapy can be a good option.

  • Practice self-care. Taking care of your needs is vital for feeling better. Self-care looks different to everyone, so focus on what makes you feel good, whether it’s hitting the gym, journaling, or surrounding yourself with friends you can lean on.

Read next: The Best Medication for Depression

Get answers to frequently asked questions about who can prescribe antidepressants.

Who can prescribe antidepressant medication?

Primary care providers, nurse practitioners, and psychiatrists can prescribe antidepressant medication following a mental health evaluation. In most states, counselors, therapists, psychologists, and social workers cannot prescribe antidepressants.

Can you get antidepressants without a psychiatrist?

You can get a prescription for antidepressants from a licensed healthcare provider other than a psychiatrist, as long as they’re qualified to write one. Other medical professionals who can prescribe antidepressants include psychiatric nurse practitioners and primary care physicians.

What do you need to qualify for antidepressants?

Your healthcare provider will make the final decision about whether you qualify for antidepressants, but if you have ongoing symptoms of depression that interfere with your daily life, they might suggest medication. This includes feelings of hopelessness or emptiness, persistent sadness, and loss of interest in activities you used to enjoy.

Read next: Depression vs. Burnout: How to Tell the Difference  

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards.

8 Sources

  1. National Institute of Mental Health. (NIMH). (2024). Anxiety disorders. https://www.nimh.nih.gov/health/topics/anxiety-disorders
  2. National Institute of Mental Health (NIMH). (n.d.). Any anxiety disorder. https://www.nimh.nih.gov/health/statistics/any-anxiety-disorder
  3. National Institute of Mental Health (NIMH). (2024). Caring for your mental health. https://www.nimh.nih.gov/health/topics/caring-for-your-mental-health
  4. National Institute of Mental Health (NIMH). (2024). Depression. https://www.nimh.nih.gov/health/topics/depression
  5. National Institute of Mental Health (NIMH). (2023). Mental health medications. https://www.nimh.nih.gov/health/topics/mental-health-medications
  6. National Institute of Mental Health (NIMH). (2024). Mental illness. https://www.nimh.nih.gov/health/statistics/mental-illness
  7. Nichol JR, et al. (2024). Medical history. https://www.ncbi.nlm.nih.gov/books/NBK534249/
  8. Sheffler ZM, et al. (2023). Antidepressants. https://www.ncbi.nlm.nih.gov/books/NBK538182/
Editorial Standards

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at blog@forhims.com!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

Daniel Z. Lieberman, MD

Education

Training

Medical Licenses

  • District of Columbia, 1996

  • Maryland, 2022

  • Virginia, 2022

Board Certifications

Other Certificates & Certifications

Affiliations & Memberships

Specialties & Areas of Focus

  • Mental Health

Years of Experience

  • 33

Previous Work Experience

Publications & Research

Media Mentions & Features

Why I Practice Medicine

  • I practice medicine because I believe that mental health is the foundation of a meaningful life. When people suffer psychologically, it touches every part of their existence—from relationships to work to the simple ability to feel joy. Because it can be so difficult for people who are suffering to find good mental health care, my mission has been to expand access through technology, so that no one is left behind.

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  • danielzlieberman.com

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