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Your First Month of Weight Loss by Hers: What to Expect
Your personalized weight loss treatment plan has been developed with doctors who have decades of experience in weight management.
To help mitigate side effects as you start treatment, your provider will typically recommend starting at a lower dose. Your dose will gradually increase over time as recommended by your provider until you reach the full dosage that your provider determines is appropriate for you.
Compounded semaglutide is injected once a week, and should be stored in the refrigerator. Once the lid is punctured, the medication will expire in 28 days.
Here’s what you can expect as you get started:
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Week 1
You’ll have received your welcome box with everything you need to inject. You’ll start with your first injection at a lower dose to minimize side effects and ease your body into treatment. You may experience side effects like heartburn, constipation, and nausea that can be addressed with over-the-counter remedies.
The most common side effects of compounded semaglutide include:
Nausea
Heartburn
Constipation
If you have any concerns about your side effects, you can chat with your provider through the app. Providers may recommend drinking plenty of water, adding fiber to your diet, and avoiding foods that increase stomach acid to minimize side effects. The app also includes recipes and mental health content to support you as you go through treatment.
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Week 2
Your second injection will be at the same lower dose as Week 1. If you experienced side effects with your first injection, you may feel them again. You’ll have your first check-in where you can share how you’re feeling and a provider can make any necessary adjustments to your treatment.
Week 3
You will take your third injection at the same lower dose this week, and may notice your appetite start to feel more controlled.
Week 4
This is typically your last injection at the lowest dose. Beginning in Week 5, you’ll likely take a higher dose as determined by your provider. You’ll also have your second check-in to ensure you’re on track and feeling confident about your treatment plan.
Compounded semaglutide is not FDA-approved. The FDA does not evaluate compounded products for safety, effectiveness, or quality.
The information provided here is not medical advice and is for informational purposes only. Please contact your provider if you have any further questions regarding your condition or treatment.
This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.
Mike Bohl, MD
Dr. Mike Bohl is a licensed physician and the Director of Medical Content & Authority at Hims & Hers. Prior to joining Hims & Hers, Dr. Bohl worked in digital health at Ro, focusing on patient education, and as the Director of Scientific & Medical Content at a stealth biotech PBC, working on pharmaceutical drug development. He has also worked in medical journalism for The Dr. Oz Show (receiving recognition for contributions from the National Academy of Television Arts and Sciences when the show won Outstanding Informative Talk Show at the 2016–2017 Daytime Emmy® Awards) and at Sharecare, and he is a Medical Expert Board Member at Eat This, Not That!.
Dr. Bohl obtained his Bachelor of Arts and Doctor of Medicine from Brown University, his Master of Business Administration and Master of Science in Healthcare Leadership from Cornell University, his Master of Public Health from Columbia University, and his Master of Liberal Arts in Extension Studies—Journalism from Harvard University. Dr. Bohl trained in internal medicine with a focus on community health at NYU Langone Health.
Dr. Bohl is Certified in Public Health by the National Board of Public Health Examiners, Medical Writer Certified by the American Medical Writers Association, a certified Editor in the Life Sciences by the Board of Editors in the Life Sciences, a Certified Personal Trainer and Certified Nutrition Coach by the National Academy of Sports Medicine, and a Board Certified Medical Affairs Specialist by the Accreditation Council for Medical Affairs. He has graduate certificates in Digital Storytelling and Marketing Management & Digital Strategy from Harvard Extension School and certificates in Business Law and Corporate Governance from Cornell Law School.
In addition to his written work, Dr. Bohl has experience creating medical segments for radio and producing patient education videos. He has also spent time conducting orthopaedic and biomaterial research at Case Western Reserve University and University Hospitals of Cleveland and practicing clinically as a general practitioner on international medical aid projects with Medical Ministry International.
Dr. Bohl lives in Manhattan and enjoys biking, resistance training, sailing, scuba diving, skiing, tennis, and traveling. You can find Dr. Bohl on LinkedIn for more information.
Publications
Younesi, M., Knapik, D. M., Cumsky, J., Donmez, B. O., He, P., Islam, A., Learn, G., McClellan, P., Bohl, M., Gillespie, R. J., & Akkus, O. (2017). Effects of PDGF-BB delivery from heparinized collagen sutures on the healing of lacerated chicken flexor tendon in vivo. Acta biomaterialia, 63, 200–209. https://www.sciencedirect.com/science/article/abs/pii/S1742706117305652?via%3Dihub
Gebhart, J. J., Weinberg, D. S., Bohl, M. S., & Liu, R. W. (2016). Relationship between pelvic incidence and osteoarthritis of the hip. Bone & joint research, 5(2), 66–72. https://boneandjoint.org.uk/Article/10.1302/2046-3758.52.2000552
Gebhart, J. J., Bohl, M. S., Weinberg, D. S., Cooperman, D. R., & Liu, R. W. (2015). Pelvic Incidence and Acetabular Version in Slipped Capital Femoral Epiphysis. Journal of pediatric orthopedics, 35(6), 565–570. https://journals.lww.com/pedorthopaedics/abstract/2015/09000/pelvic_incidence_and_acetabular_version_in_slipped.5.aspx
Islam, A., Bohl, M. S., Tsai, A. G., Younesi, M., Gillespie, R., & Akkus, O. (2015). Biomechanical evaluation of a novel suturing scheme for grafting load-bearing collagen scaffolds for rotator cuff repair. Clinical biomechanics (Bristol, Avon), 30(7), 669–675. https://www.clinbiomech.com/article/S0268-0033(15)00143-6/fulltext
