View weight loss medications

Get started

The Perfect Blueberry Smoothie: Antioxidants, Protein & Energy in a Glass

Dr. Felix Gussone

Reviewed by Felix Gussone, MD

Written by Lauren Panoff

Published 05/07/2025

What you eat in the morning could very well set the tone for the rest of your day.

If you’re on the hunt for a refreshing morning beverage that takes five minutes to make and can double as a last-minute healthy breakfast recipe, how about a blueberry smoothie? 

Not only is this drink pretty enough for the gram (hello, purple glow), but it’s also packed with nutrients that actually do your body good — like supporting your brain, gut, and energy levels.

Whether you’re powering through meetings, chasing a toddler around the living room, or just need something simple and tasty between all the things, a blueberry smoothie might be the easiest health upgrade you make this week.

Sure, smoothies might be a bit of a health cliche, but when they’re made right (with plenty of whole foods and not junky ingredients), they can deliver.

A healthful  blueberry smoothie, in particular, might surprise you with how much it has to offer. There’s a significant amount of evidence that eating more blueberries can benefit our heart, brain, blood sugar regulation, energy, and more.

1. Packed with Important Nutrients

Tiny as they may be, blueberries are a nutritional powerhouse.

They boast vitamin C for great skin and immune function, manganese for bones and metabolism, and a nice dose of dietary fiber — an essential nutrient most people are lacking.

When you blend blueberries with ingredients like yogurt, greens, soy milk, or almond butter, you're not just making a smoothie — you’re building a nutritional masterpiece that supports energy, immunity, and overall health.

Incorporating a protein source, like yogurt, cottage cheese, tofu, or nut butter can also help support muscle recovery and satiety. 

2. High in Antioxidants

These little blue gems are basically your body's cleanup crew. Thanks to their rich supply of antioxidants — especially anthocyanins — blueberries help protect your cells from damage caused by everyday stress and aging. 

Studies suggest the anthocyanins in blueberries may support brain function, memory, and heart health over time. One study found that blueberries had the highest anthocyanin content among all berries. Blueberries are the MVP.

Pro tip: For even more antioxidants per serving, look for wild blueberries in the fresh or frozen section. 

3. Supports Digestive Health 

If your digestion is, well, less than regular, blueberries might help.

They’re naturally high in fiber, which keeps things moving along and supports your gut microbiome, which is the community of microbes living in your digestive tract and keeping you healthy. 

Blueberries have been shown to help improve intestinal health and the integrity of your gut by fighting oxidative stress, reducing gut inflammation, and supporting friendly microbes.

When paired with yogurt, your smoothie becomes a double threat in the best way possible: The prebiotics from the berries and probiotics from the yogurt create a gut-loving combo your digestive system will appreciate.

4. Promotes Brain and Heart Health

Blueberries are multitaskers when it comes to keeping your heart and brain in check.

Their antioxidant and anti-inflammatory properties may help lower blood pressure and improve blood vessel function while also supporting memory and cognitive performance.

A small systematic review and meta-analysis of 14 randomized controlled trials found that blueberry consumption was associated with better cognitive function and mood stability.

In a double-blind, randomized, placebo-controlled trial among older adults, researchers found that eating wild blueberries for six months improved the speed of information processing and overall cognitive function. 

Additionally, blueberries have been shown to enhance nitric oxide production in the body, which helps keep your blood vessels dilated and healthier. This translates to better circulation, which supports healthy blood pressure levels and a reduced risk of heart disease.

5. Helps Curb Cravings and Boost Energy

Thanks to their fiber content and natural sweetness, blueberries help you feel full without the sugar crash that follows, say, downing a glass of orange juice.

Some research shows that eating blueberries can help reduce postprandial (after eating) blood sugar levels and insulin concentrations. They may even help reduce the overall risk of pre-diabetes and type 2 diabetes.

When blended with protein and fat (like yogurt and nut butter), your smoothie becomes a satisfying mini-meal that helps regulate blood sugar and keeps those snacky cravings from creeping in 20 minutes later.

So you're ready to blend up some blueberry magic. Curious about what ingredients to add to your blueberry smoothie that are both nutritious and delicious?  The goal is to create something that tastes great, keeps you full, and doesn’t spike your blood sugar an hour later. 

Here’s a smart lineup of ingredients to get you started. Mix and match to your liking:

  • Frozen blueberries. These are the stars of the show, packed with antioxidants, fiber, and natural sweetness. Using frozen berries also gives your smoothie that creamy, milkshake-like texture without adding ice.

  • Unsweetened non-dairy milk. This is your liquid base, and the choice is yours — almond, oat, soy, pea, or cashew. Just be sure to go unsweetened to avoid unnecessary added sugar. (Note: soy or pea milk provides the most protein per serving). 

  • Greek yogurt or plant-based yogurt. Adds creaminess, protein, and gut-friendly probiotics to keep you satisfied longer. Go for plain varieties to keep sugar in check and let the blueberries shine.

  • Silken tofu. Hear us out: Silken tofu (read: not extra firm) is creamy and literally falls apart in your hands, making it super blendable. It’s also a great source of protein and comes with a neutral flavor that won’t overpower your smoothie.

  • Leafy greens. Blueberries blend well with leafy greens like spinach or kale, which can be a game-changer for those who want a salad alternative. Leafy greens are chock full of vitamins, minerals, fiber, and antioxidants of their own, making this combo quite the dynamic duo. 

  • Pitted dates. Toss in one or two dates (remove the pits first) for a naturally sweet, caramel-like flavor to balance out the tartness of other ingredients. 

  • Nut butter. A spoonful adds healthy fats, a subtle nutty flavor, and extra staying power. It’s a simple way to boost satiety and keep those 10 a.m. snack cravings at bay. Try peanut butter, cashew, almond, sunflower, or even walnut butter. 

  • Banana (optional, for sweetness). If you like your smoothie a bit sweeter, half a banana does the trick — no added sugars necessary. It also adds potassium and fiber for an extra nutrient bonus. If you don’t eat all of your bananas before they go brown, peel and store them, halved, in the fridge for times like these. Frozen bananas will add extra creaminess.

  • Chia or ground flax seeds. These tiny powerhouses provide fiber and omega-3s, and they help thicken your smoothie. They also support digestion and promote blood sugar stability. Studies show that they have better nutrient absorption and digestibility when ground versus whole, so blend them right in. 

  • Vanilla or cinnamon (optional). A splash of vanilla extract or a dash of cinnamon adds flavor without the calories. Bonus: cinnamon may even help with blood sugar control.

  • Protein powder (optional). You can get protein from whole food sources like nut butter, seeds, or tofu, but a scoop of protein powder can also quickly add 20-30 grams to your smoothie. For help choosing the best type of protein powder for you check out our guide. 

Blend your chosen ingredients together until smooth, pour into your favorite cup, and you’ve got a blueberry smoothie that tastes good and feels even better.

Want even more customization for your delicious smoothie? Here are some winning combos to help you create exactly what you’re craving:

Your Goal
Add These Ingredients
More protein
Greek yogurt, cottage cheese, protein powder, soy milk, hemp seeds
Creamier texture
Half an avocado, frozen banana, silken tofu, canned coconut milk
Extra fiber
Ground flax seeds, chia seeds, spinach, oats, handful of cashews
Naturally sweet
Banana slices, frozen mango chunks, pitted dates, maple syrup
More healthy fats
Walnuts, cashews, nut butter
Antioxidant boost
Raspberries, blackberries, strawberries, leafy greens
Digestive support
Ginger, kefir, probiotic yogurt (says it contains live and active cultures)
Energy balance
Cinnamon, seeds, and incorporating a healthy fat and protein source for slower digestion/satiety

Blueberry Smoothie Recipe

Looking for something simple? This blueberry smoothie recipe, which has minimal prep time and requires only four ingredients, will do the trick.

To make this blueberry smoothie recipe, all you need is frozen blueberries, unsweetened vanilla almond milk, chia seeds, and vanilla protein powder.

Blend everything together, adding more milk (or water) or ice cubes as needed to achieve your desired consistency, and enjoy.

Turn it Into a Smoothie Bowl

Want to upgrade your smoothie to something you can eat with a spoon? Just reduce the liquid a bit when blending to get a thicker consistency.

Then, pour it into a bowl and add toppings like:

  • Fresh blueberries, raspberries, freeze-dried strawberries, or sliced bananas
    Granola

  • Chia seeds or hemp hearts

  • Nut butter drizzle

  • Coconut flakes or cacao nibs for crunch

Whether you're blending breakfast or crafting the perfect post-workout snack, a blueberry smoothie can be as nourishing as it is delicious. The key is to strike the right balance of ingredients to keep you energized and satisfied — without the sugar crash.
Keep these quick tips in mind for best smoothie success:

  • Aim for balance. Include a source of protein, fiber, and healthy fats to create a smoothie that fuels you for hours.

  • Watch the sugar. Stick with natural sweeteners like bananas or dates, and skip the added syrups or sweetened yogurts.

  • Customize to your needs. Adjust ingredients based on your personal goals, whether that’s extra protein, more fiber, or just a creamy texture you love.

For more healthy recipes to start your day off strong, try our overnight oats, hormone balance smoothies, or this healthy matcha latte.

9 Sources

  1. Hanna M, et al. (2022). B vitamins: functions and uses in medicine. https://pmc.ncbi.nlm.nih.gov/articles/PMC9662251/
  2. Huth PJ, et al. (2015). A systematic review of high-oleic vegetable oil substitutions for other fats and oils on cardiovascular disease risk factors: implications for novel high-oleic soybean oils. https://pmc.ncbi.nlm.nih.gov/articles/PMC4642420/
  3. Kranthi Vanga S, et al. (2017). How well do plant based alternatives fare nutritionally compared to cow’s milk?. https://pmc.ncbi.nlm.nih.gov/articles/PMC5756203/
  4. National Celiac Association (NCA). (2022). Is it safe to consume oatmilk?. https://nationalceliac.org/celiac-disease-questions/is-it-safe-to-consume-oatmilk/
  5. Ramsing R, et al. (2023). Dairy and plant-based milks: implications for nutrition and planetary health. https://pmc.ncbi.nlm.nih.gov/articles/PMC10504201/
  6. Ritchie R. (2022). Dairy vs. plant-based milk: what are the environmental impacts?. https://ourworldindata.org/environmental-impact-milks
  7. Shkembi B, et al. (2023). Glycemic responses of milk and plant-based drinks: food matrix effects. https://pmc.ncbi.nlm.nih.gov/articles/PMC9914410/
  8. University of Florida, Institute of Food and Agricultural Sciences (IFAS). (n.d). Plant-based milks: almond. https://edis.ifas.ufl.edu/publication/FS410
  9. Yu Y, et al. (2023). Oat milk analogue versus traditional milk: comprehensive evaluation of scientific evidence for processing techniques and health effects. https://pmc.ncbi.nlm.nih.gov/articles/PMC10534225/
Editorial Standards

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

Felix Gussone, MD

Dr. Felix Gussone is a medical content specialist and Medical Advisor at . Prior to joining Hims & Hers, Felix worked in digital health at , focusing on patient education.

Raised in Germany, Dr. Gussone earned his M.D. from Ludwig-Maximilians-University before transitioning into health journalism and medical education content. He currently leads the medical information content team at an American biotech company.

Throughout his career, Dr. Gussone has used his medical expertise to drive the development of evidence-based health content and patient education materials. He has over 10 years of experience covering a wide range of topics, including health news, diet and weight loss, mental health, and sexual health, for prominent television programs and online publications.

Dr. Gussone has contributed to leading television programs such as CNN’s Anderson Cooper 360, NBC TODAY, and NBC Nightly News with Lester Holt, where he produced and wrote a wide range of health and wellness stories for television and digital outlets that engaged and informed diverse audiences across the United States and abroad. In addition to his work in cable and network health reporting, Felix served as Senior Health Editor at Elemental, Medium’s health and wellness publication, where he led editorial content development focused on science and personal well-being.

Dr. Gussone lives in Cambridge, Massachusetts and Brooklyn, and enjoys perfume making, scuba diving, roller blading, and traveling. You can find Dr. Gussone on LinkedIn for more information.

Read more

Related Articles