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Are Meal Replacement Shakes Healthy?

Craig Primack MD

Reviewed by Craig Primack, MD, FACP, FAAP, FOMA

Written by Hadley Mendelsohn

Published 02/13/2025

Let’s be real — meal replacement shakes can be a game-changer when you’re short on time or just not in the mood to cook. But are meal replacement shakes healthy? Well…it depends.

Some are packed with protein, fiber, and essential vitamins to fuel you efficiently. Some, on the other hand, are more like glorified milkshakes loaded with sugar and fillers.

The TL;DR? Meal replacement shakes can be healthy when you know how to spot the difference. Choosing the right meal replacement shakes can be a great way to work toward weight loss goals without sacrificing nutrition or overshooting your daily calorie target.

We’ll break down what to look for (and what to avoid) in a meal replacement shake so you can sip smarter and stay on track.

Meal replacement shakes, protein shakes, and smoothies may sound similar, but they’re not all the same. Meal replacement drinks are specifically designed to replace a meal, typically breakfast or lunch. They usually come in powder form — you just mix them with water, ice, or occasionally your milk of choice.

Unlike fresh smoothies, protein shakes don’t always contain whole fruits and veggies. But the best meal replacement shakes still deliver essential nutrients like protein, vitamins, and minerals to keep you full and energized — without excess sugar or empty calories.

Some shakes use plant-based proteins, while others rely on dairy-based options. Many also include various supplements tailored to different health goals.

A balanced diet rich in whole foods for at least some meals is key to staying healthy. For most meals, try to fill your plate with:

  • Vegetables and leafy greens, like spinach, kale, broccoli, and peppers

  • Fruits, such as berries, bananas, and citrus

  • Whole grains, like quinoa, farro, brown rice, and whole-wheat bread

  • Lean proteins, including chicken, turkey, fish, tofu, eggs, and Greek yogurt

  • Legumes, such as beans, lentils, chickpeas, and edamame

  • Nuts and seeds, like almonds, walnuts, chia seeds, and flaxseeds

But if we’re being honest, life doesn’t always make it easy to sit down for three balanced meals a day. Whether you’re rushing through a packed schedule or dealing with a lower appetite from weight loss meds, a high-quality meal replacement shake can help bridge the gap without skimping on nutrition.

When are meal replacement shakes healthy? Meal replacement shakes can be a powerful tool in your weight loss eating plan — especially when they’re packed with protein.

A large review of studies found that people with overweight and obesity who use meal replacements lost more weight over a year than folks on other diets. Adding support (like coaching) makes them even more effective.

But how do protein-rich meal replacement shakes actually help with weight loss? Let’s break down the nitty-gritty.

  • Protein shakes can help build and maintain muscle. Protein is key for preserving lean muscle while losing weight, especially when combined with strength training routines like bodyweight exercises or weightlifting.

  • They may speed up metabolism. Having more muscle means burning more calories, even at rest — making weight loss a little easier.

  • They can curb appetite. Protein helps with satiety (a feeling of fullness), which can help you avoid overeating and work on portion control.

  • They might control cravings. A high-protein breakfast has been shown to reduce cravings later in the day, and a meal replacement shake could have a similar effect if it’s high-protein.

  • They can be low-calorie. Some meal replacement shakes have fewer calories than you’d get from a full meal while still filling you up with good ingredients.

High-protein diets are also linked to reduced belly fat and may help prevent weight regain after weight loss.

The Dietary Guidelines for Americans recommend 46 grams of protein per day for women and 56 grams for men. But aiming for around 100 grams (or sometimes more) daily may offer even greater benefits.

Weight loss meal replacement shakes that balance protein and fiber can help you hit your targets — and having a quick, nutritious option makes it easier to stay on track.

So, we’ve covered the benefits of protein-packed weight loss shakes, but they aren’t perfect — and not all are created equal.

Here are a few things to watch out for so you can make the most of our meal replacement shakes and reap their benefits:

  • Check for high calories. If weight loss is the goal, you should be trying to maintain a calorie deficit (a fancy way of saying you’re taking in fewer calories than you burn). Some protein shakes — especially high-calorie ones — can tip the scale in the wrong direction if not factored into your overall daily calorie intake. Shoot for options with between 150 to 250 calories per serving.

  • Scan for added sugars and artificial ingredients. Some shakes are loaded with sweeteners and refined carbs, which can contribute to weight gain since they tack on more calories and sugar without satiating you. Reach for high-quality meal replacement shakes with real food ingredients and high-fiber content to balance simple carbohydrates.

  • Load up on essential vitamins and minerals. Not all meal replacement shakes provide the vitamins and minerals your body needs. It’s especially important to make sure you’re getting essential nutrients if you’re cutting back on calories or if you have a reduced appetite from weight loss meds. Look out for meal replacement shakes that have a good range of macronutrients (protein, fat, and carbs) and micronutrients — like calcium, folate, iron, manganese, and zinc.

  • Listen to your body. Too much protein or fiber can lead to bloating, gas, and other tummy troubles. Take it slow and listen to your body to see how you respond if you’re new to the world of protein shakes and bars.

To make sure you’re having a meal replacement shake that supports a healthy weight, keep these key factors in mind.

1. Know Your Proteins

Protein powder is usually the star ingredient of a meal replacement shake (and one of the MVPs of a healthy diet). There are lots of different types. Here’s a quick breakdown:

  • Whey protein is a fast-digesting milk protein that helps build lean muscle. It’s a good source of essential amino acids.

  • Casein protein is another milk protein that digests more slowly and can keep you feeling full longer. It’s also a good source of essential amino acids.

  • Soy protein is a plant-based protein with all nine essential amino acids.

  • Pea protein is a stellar plant-based option that may help curb appetite.

  • Hemp and brown rice proteins are often combined in shakes and bars to create a complete amino acid profile.

  • Collagen protein is also sourced from animals (bovine) and is often linked to skin and joint health. But it doesn’t supply all the essential amino acids.

2. Look Out for Other Healthy Nutrients

A good meal replacement shake should do more than just pack in protein — it should also provide a well-rounded nutritional profile with:

  • Fiber. Aim for at least 3 to 5 grams of fiber per serving to support gut health and keep blood sugar stable.

  • Healthy fats. Unsaturated fats from ingredients like nuts, seeds, or coconut help keep you satisfied and support overall health.

  • Essential vitamins and minerals. If you’re replacing a full meal, make sure your shake contains important micronutrients, like antioxidants.

3. Avoid Artificial Ingredients and Additives

Some meal replacement shakes sneak in lots of sugar while skimping on protein content. To dodge those traps, read the label carefully to check for:

  • Added sugars. Ingredients like corn syrup, cane sugar, agave, or honey can spike blood sugar and add unnecessary calories.

  • Artificial preservatives and additives. Synthetic flavors, dyes, and non-nutritive sweeteners don’t add nutritional value — but they may help keep calories low while preserving taste.

  • Sugar alcohols. Xylitol, maltitol, sorbitol, and other sugar alcohols can cause bloating and digestive discomfort in some people.

Try Hers Meal Replacement Shakes for Weight Loss

Hers vanilla meal replacement shake is designed to be nutrient-dense, filling, and low-calorie.

It’s also a full-on treat, thanks to the marshmallowy vanilla taste — and it’s super easy to make. You don’t even need a blender (unless you want to blend up some ice). All you have to do is scoop in a serving, add water, stir, and sip.

One serving contains 200 calories, 6 grams of fat, 13 grams of carbohydrates, 3 grams of fiber, 2 grams of sugar, and 27 grams of protein, plus a variety of vitamins and minerals.

If you’re looking for a quick and healthy way to replace a complete meal, these easy protein shakes for weight loss fit the bill.

There’s no one-size-fits-all weight loss journey — what works for one person might look different for another. And while healthy eating habits play a big role, other lifestyle factors matter, too.

Lifestyle Changes to Boost Weight Loss

  • Exercise regularly. Aim for at least 150 minutes of exercise per week, including a couple of strength training sessions. Lifting weights can help boost metabolism and improve body composition.

  • Get enough quality sleep. Getting seven to nine hours of quality shut-eye each night can support metabolism and hunger regulation. Our sleep hygiene tips can help you get there.

  • Drink plenty of water. Staying hydrated helps you feel full and can make it easier to cut back on sugary drinks and alcohol.

  • Try to manage stress. Chronic stress can affect hormones linked to appetite and weight gain. Finding ways to relax — whether through meditation, movement, or seeing friends more — can make a difference.

Pairing these habits with healthy meal replacement shakes and other mindful choices can create a well-rounded approach to weight management. And for some people, additional support through weight loss medications may be worth exploring.

Medications for Weight Loss

Lifestyle changes alone don’t always lead to the results some people need. If you’re living with excess weight or obesity, weight loss medications like GLP-1s might be an option.

GLP-1s mimic a natural hormone that slows digestion, which can keep you fuller longer and make portion control easier. If you’re curious whether these meds might be a good fit for you, a healthcare provider through Hers can help you explore your options.

Meal replacement shakes and smoothies can be a simple, nutritious way to support weight loss — whether or not you’re taking GLP-1 medications. The key is choosing wisely:

  • Look for shakes high in protein and fiber, with minimal added sugars and artificial ingredients.

  • Prioritize weight loss meal replacement shakes that provide essential vitamins and minerals to help fill nutritional gaps.

  • Remember, whole foods should always be the foundation of your diet, but a well-chosen shake can be a smart, convenient addition.

If you’re looking for more guidance and support or unsure how to incorporate meal replacement shakes into your routine, a registered dietitian or nutritionist can help you create a plan that supports your goals.

And if you’re on (or considering) weight loss medication, Hers offers meal replacement shakes designed specifically for GLP-1 users. A Hers healthcare provider can guide you on how to include them as part of your weight loss program.

20 Sources

  1. Abou-Samra RA, et al. (2011). Effect of different protein sources on satiation and short-term satiety when consumed as a starter. https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-10-139
  2. Astbury NE, et al. (2019). A systematic review and meta-analysis of the effectiveness of meal replacements for weight loss. https://pubmed.ncbi.nlm.nih.gov/30675990/
  3. Burls AM, et al. (2019). Drinking extra water or other non‐caloric beverages for promoting weight loss or preventing weight gain. https://pmc.ncbi.nlm.nih.gov/articles/PMC6426280/
  4. Carbone JO, et al. (2019). Dietary protein and muscle mass: translating science to application and health benefit. https://pmc.ncbi.nlm.nih.gov/articles/PMC6566799/
  5. Centers for Disease Control and Prevention (CDC). (2023). Adult activity: an overview. https://www.cdc.gov/physical-activity-basics/guidelines/adults.html
  6. Centers for Disease Control and Prevention (CDC). (2023). Tips for healthy eating for a healthy weight. https://www.cdc.gov/healthy-weight-growth/healthy-eating/index.html
  7. Damaghi MA, et al (2021). Comparison of the effect of soya protein and whey protein on body composition: a meta-analysis of randomised clinical trials. https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/comparison-of-the-effect-of-soya-protein-and-whey-protein-on-body-composition-a-metaanalysis-of-randomised-clinical-trials/EEBA262CE261735D73E51A4328132F3F
  8. Hoertel HE, et al. (2014). A randomized crossover, pilot study examining the effects of a normal protein vs. high protein breakfast on food cravings and reward signals in overweight/obese “breakfast skipping”, late-adolescent girls. https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-13-80
  9. Kim JO. (2020). Pre-sleep casein protein ingestion: new paradigm in post-exercise recovery nutrition. https://pubmed.ncbi.nlm.nih.gov/32698256/
  10. Lopez MI, et al. (2024). Biochemistry, essential amino acids. https://www.ncbi.nlm.nih.gov/books/NBK557845/
  11. MacKenzie-Shalders KR, et al. (2020). The effect of exercise interventions on resting metabolic rate: A systematic review and meta-analysis. https://www.tandfonline.com/doi/abs/10.1080/02640414.2020.1754716
  12. Mäkinen KA. (2016). Gastrointestinal disturbances associated with the consumption of sugar alcohols with special consideration of xylitol: Scientific review and instructions for dentists and other health-care professionals. https://pmc.ncbi.nlm.nih.gov/articles/PMC5093271/
  13. Michelfelder AA. (2009). Soy: a complete source of protein. https://pubmed.ncbi.nlm.nih.gov/19145965/
  14. Moon JA, et al. (2020). Clinical evidence and mechanisms of high-Protein diet-induced weight loss. https://pmc.ncbi.nlm.nih.gov/articles/PMC7539343/
  15. National Library of Medicine. (2022). Muscle cells vs. fat cells. https://medlineplus.gov/ency/imagepages/19495.htm
  16. Pu SZ, et al. (2023). Effects of oral collagen for skin anti-aging: a systematic review and meta-analysis. https://pmc.ncbi.nlm.nih.gov/articles/PMC10180699/
  17. Schaefer CH, et al. (2015). User’s guide to mechanism of action and clinical use of GLP-1 receptor agonists. https://pubmed.ncbi.nlm.nih.gov/26371721/
  18. U.S. Department of Agriculture. Dietary Guidelines for Americans, 2020-2025. https://www.dietaryguidelines.gov/sites/default/files/2020-12/Dietary_Guidelines_for_Americans_2020-2025.pdf
  19. Veldhorst M, et al. (2008). Protein-induced satiety: effects and mechanisms of different proteins. https://pubmed.ncbi.nlm.nih.gov/18282589/
  20. Wu SH, et al. (2022). Effect of dietary protein and processing on gut microbiota—a systematic review. https://pmc.ncbi.nlm.nih.gov/articles/PMC8840478/
Editorial Standards

Hims & Hers has strict sourcing guidelines to ensure our content is accurate and current. We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. See a mistake? Let us know at [email protected]!

This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment. Learn more about our editorial standards here.

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