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Kidney health

Blood Urea Nitrogen

Also known as: Urea nitrogen test, Serum urea nitrogen, Blood urea test

A blood urea nitrogen (BUN) test measures the amount of urea nitrogen in your blood. Urea is a waste product made in your liver when protein is broken down into amino acids and then converted into ammonia and urea. Your kidneys filter urea out of your blood and remove it through your urine.

Because both your liver and kidneys play roles in processing and clearing urea, the BUN test helps evaluate how well these organs are functioning. It is most commonly used to assess kidney (renal) function, especially when paired with serum creatinine.

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Key takeaways

  • Sample required: Blood

  • Tests for: How effectively your kidneys remove waste from your bloodstream

  • Typical healthy range: 7 to 20 milligrams per deciliter (mg/dL); may vary slightly by lab, age, diet, and health status

What can a BUN test tell you?

The BUN test helps assess how efficiently your kidneys remove waste and can also provide clues about your hydration status, protein metabolism, and liver function. When interpreted with creatinine and the BUN-to-creatinine ratio, it helps identify whether kidney dysfunction is due to dehydration, intrinsic kidney disease, or obstruction.

What is being tested?

The BUN test measures urea nitrogen, a byproduct of protein metabolism. Your body breaks down dietary proteins into amino acids, which produces ammonia. Your liver then converts ammonia to urea, a less toxic compound, and your kidneys filter urea from your blood so it can be excreted through your urine.

If the kidneys are under-functioning or blood flow to them is reduced, urea builds up in the blood, raising BUN levels. Conversely, if liver function is compromised, urea production declines, lowering BUN.

Because diet, hydration, and liver function influence BUN, providers interpret it alongside serum creatinine and the BUN/creatinine ratio for a fuller assessment of kidney function.

Where is the BUN test typically included?

The BUN test is a standard part of basic and comprehensive metabolic panels (BMP and CMP).

Rarely, BUN may also be ordered separately to monitor known kidney conditions, hydration levels, or response to treatment.

BUN testing is included as part of lab testing through Hers, which goes beyond standard lab tests to help you understand what’s really going on in your body and either address or get ahead of problem areas with a tailored action plan.

Who should get a BUN test?

Providers may order a BUN test if you have potential symptoms of kidney dysfunction, such as fatigue, swelling in the legs or ankles, or changes in urine output.

You may also need this test if you take certain medications that affect the kidneys or you’re at higher risk for kidney disease, especially if you have diabetes, high blood pressure, heart disease, or a family history of kidney issues.

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Not available in all 50 states. Eligibility and provider order required. Lab results alone are not intended to diagnose, treat, or cure any condition. A provider will reach out about critical results and plans include access to 24/7 provider messaging.

Images for illustrative purposes only.

Frequently asked questions

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What causes changes in BUN levels?

Elevated BUN levels may be caused by kidney dysfunction or failure, dehydration, heart failure, excess dietary protein, gastrointestinal bleeding, or catabolic states (infection, fever, trauma).

Low BUN may be due to severe liver dysfunction, protein deficiency, overhydration, or SIADH (syndrome of inappropriate antidiuretic hormone).

Is fasting required?

No fasting is necessary. Staying hydrated before your blood draw may help ensure accurate results.

How long do results take?

Most labs return BUN results within 24 to 48 hours.

Can I test BUN at home?

Some at-home kits include BUN as part of metabolic panels, but results must be reviewed by a licensed provider.

How often should I test?

Most adults have BUN checked during annual physicals. Those with kidney disease, high blood pressure, or diabetes may need more frequent testing.

Does insurance cover the test?

Yes, when ordered for medical reasons or as part of routine metabolic monitoring. Insurance is not required with lab testing through Hers.

What tests are related to this biomarker?

• Serum creatinine

BUN/creatinine ratio

Estimated glomerular filtration rate (eGFR)

• Urinalysis

• Comprehensive metabolic panel (CMP)

• Basic metabolic panel (BMP)

The information provided here is for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always talk to a qualified healthcare provider about your specific health concerns.

Related biomarkers

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BUN/Creatinine Ratio

This marker compares protein waste (BUN) and creatinine to give a reading on hydration and protein metabolism. A normal ratio suggests healthy fluid balance and that your kidneys are handling protein waste well.

Learn more about BUN/Creatinine Ratio

Creatinine

Creatinine is a waste product from muscle activity, like exercise, that the kidneys filter out of the blood. A normal Creatinine level shows that the kidneys are working well and doing a good job of filtering.

Learn more about Creatinine

Estimated Glomerular Filtration Rate (eGFR)

Estimated glomerular filtration rate (eGFR) measures how well your kidneys filter blood each minute. Healthy levels mean your kidneys are effectively removing waste and balancing fluids.

Learn more about Estimated Glomerular Filtration Rate (eGFR)

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Reviewed by Darragh O'Carroll, MD

Published 12/04/2025