Miley Cyrus smiling and holding a jar of skin cream

PrescriptionAcne Cream


Stops acne in its tracks


Prevents future breakouts


Custom to your skin

When you’ve tried everything on your stubborn acne, it’s time to explore a personalized prescription. Tailored to treat specific acne needs, this cream is made of a customized blend of up to five powerhouse ingredients: tretinoin, clindamycin, azelaic acid, zinc pyrithione, and niacinamide.

Product overview

What’s in this prescription cream

This customized cream is a blend of up to 5 ingredients including tretinoin, niacinamide, clindamycin phosphate, zinc pyrithione and azelaic acid. It’s available in different mixes and strengths to address specific skin and acne needs.

What it treats

This cream helps control acne breakouts, clear up clogged pores, reduce dark spots, boost firmness, create more even skin texture, smooth fine lines, and tame redness.
What to expect

How Hers works

After answering some questions about your specific skin concerns, you’ll have a consultation with a medical professional. If prescribed, your customized formula will be shipped directly to your door at the cadence of your choosing.

The purge

Some people experience “the purge” a couple weeks into treatment, where skin may feel irritated and more blemishes may appear at first. But don’t freak out—this is normal and a sign that the cream is working.

* Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.

* Do not use this medication if you are allergic to tretinoin, clindamycin, niacinamide, azelaic acid or zinc pyrithione. Common side effects of the Acne Cream which typically go away with time


So, you’ve got acne—that doesn’t mean you have to visit the dermatologist's office

The power of a prescription cream

Going prescription means effective, clinically-proven ingredients you can’t buy at the store to tackle acne head on

A customized formula

The Fingerprint Formula Method mixes a cream with ingredients specially selected by dermatologists, tailored to specific acne issues

Expert medical care

Quality medical professionals will help choose your formula, if appropriate—and are available for as many follow-ups as you need

Trusted acne-fighting ingredients,
from azelaic acid to zinc

When you get prescription acne cream through Hers, amazing things happen

Before/after images shared by customer. Customer's results have not been independently verified. Individual results will vary.

Tackling acne is easy as 1, 2, 3

Pump it out
Press out a precisely dosed amount of cream
Apply the cream
Spread a pea-sized amount over your face at night as directed by your provider, usually starting with every 2-3 nights, working up to nightly over time
Order matters
Use the prescription acne cream after cleansing, then follow it with a moisturizer afterward as needed

A comprehensive routine

The Clear Skin System with prescription acne cream

Upgrade your prescription acne cream to a complete skincare routine for better results and less irritation.
Step 1: The Deep Sea Cleanser
Gently cleanses and hydrates your skin to prep for prescription treatment
Step 2: Custom Acne Face Cream
Customized to fight your acne with clinically-proven ingredients
Step 3: Tidal Wave Moisturizer
Locks in moisture without clogging pores (thanks to hyaluronic acid)

Side effects and what to expect with our acne cream

Time to results
Most people see improvement in a few months, but this can vary. Remember to stick with it—it’s all about consistency. If you’re not satisfied, we offer a 90-day money back guarantee.
The purge
Some people experience “the purge” a couple weeks into treatment, where skin may feel irritated and more zits and pimples may appear. But don’t freak out—this is normal and a sign that the cream is working. Our hydrating Tidal Wave Moisturizer can help moisturize dry skin during this phase.
Possible side effects
The most common side effects of the acne cream are skin redness, peeling, itching, stinging and irritation, especially where the acne cream was applied. Sun exposure while using the acne cream may cause increased skin sensitivity. If you experience these side effects, tell your provider. If you are in serious pain or have signs of an allergic reaction, such as blistering at the site of applications, hives or trouble breathing, seek medical care immediately.
Requesting changes
Not seeing the progress you’d like? Your provider is just a message away. You can reach out any time for questions on your formula and request changes to ingredients or strength.

Acne cream’s team: the cleanser and moisturizer

Level up your skincare routine by adding our hydrating cleanser and lightweight moisturizer to your acne-fighting team.
Deep Sea Cleanser
  • A gentle, lightweight, hydrating cleanser perfect for acne-prone skin.
Suitable for acne-prone skin
Tidal Wave Moisturizer
  • A hydrating, gentle, non-clogging moisturizer made with hyaluronic acid and squalane
Super hydrating

We've got answers

Frequently asked questions about our acne cream

What is tretinoin?
Tretinoin is a vitamin A derivative commonly used to treat certain skin conditions like acne and aging when used topically . Topical tretinoin increases the rate of skin cell turnover, which can help to clear acne and reduce fine lines associated with aging as well as fade dark spots. Tretinoin is a powerful, prescription-only acne medication from the family of retinoids, which includes a wide variety of treatments, from the oral medication isotretinoin used to treat severe acne to over the counter retinol treatments typically used for milder skin conditions.
What is niacinamide?
Niacinamide is a form of vitamin B3 that is available in a variety of foods, oral supplements and topical creams for acne. In its topical form, niacinamide is often combined with other active ingredients in acne treatments. Niacinamide is available over the counter in facial creams and as an oral health supplement.
What is clindamycin?
Clindamycin is an antibiotic available in oral and topical forms to treat a wide range of bacterial infections. When added to facial treatments, clindamycin can be effective by reducing acne-causing bacteria. Clindamycin is available only with a prescription from a healthcare provider and is often combined with other active ingredients to treat acne, such as tretinoin or benzoyl peroxide.
What causes acne?
Acne occurs when dead skin cells and oil block hair follicles, which allows bacteria to grow and causes inflammation and irritation. There are many forms of acne, including whiteheads, blackheads, pimples and cysts. Most people experience some form of acne in their lifetime, especially teenagers and women at specific times during their menstrual cycle. Acne ranges from occasional mild breakouts to severe, painful acne that occurs regularly. Mild breakouts may be treatable with over the counter products like salicylic acid or prescription treatment containing a retinoid like tretinoin, while severe acne may require oral antibiotic therapy or an oral retinoid (e.g., isotretinoin).
What is the best treatment for acne?
The best treatment for acne depends on your skin type and the root cause of your acne. Many people find that the occasional, mild pimple or breakout can be treated with over the counter drugstore products, such as an acne spot treatment, benzoyl peroxide or salicylic acid. Recurring mild to moderate acne may require a prescription topical treatment, such as clindamycin or tretinoin. Severe acne may require an oral antibiotic or isotretinoin regimen. If you have sensitive skin or a condition like eczema or rosacea, you may need to use caution when choosing acne products. While there is not a single “best” treatment, an online or in-person consultation with a medical provider can help you to figure out what will work best for your particular situation. Click "start consultation" above to connect with a providor or read more about the best acne treatments (according to science) on our blog.
How do you apply acne cream?
Apply topical acne treatments to the affected area as directed, typically once or twice daily, to clean, dry skin. Apply the medication evenly by rubbing in gently. Before applying, cleanse the skin gently and pat dry. Applying a moisturizer after acne cream may help restore skin barrier as well as negate potential irritation from the treatment itself. If you have sensitive skin, you may need to use acne cream a few days a week at first and gradually work up to daily use.
The tretinoin in acne cream has an exfoliating effect, so there is typically no need to exfoliate your skin beyond the application of acne cream. Additionally, retinoids like tretinoin can increase your skin’s sensitivity to the sun, so be sure to wear a sunscreen of SPF 30 or higher every day while using acne cream.
What face wash and moisturizer should I use with acne cream?
Acne cream with tretinoin is an effective acne treatment cream, but it is only one part of a good acne skincare routine. While using acne cream, you will want to avoid any products that clog pores or irritate your skin to get the best results. Look for a non-comedogenic, fragrance-free cleanser and moisturizing lotion to complement your acne cream. If you have particularly oily skin, look for an oil-free cleanser.
Be sure to scan any cleanser and moisturizer for other acne-fighting ingredients, such as benzoyl peroxide, tea tree oil or glycolic acid. Combining different acne treatment ingredients could increase risk of irritation, so be sure to talk to your healthcare provider if you are experiencing redness or discomfort. When in doubt, look for a gentle cleanser and moisturizer for sensitive skin. Better yet, get the full Clear Skin System from hers for a perfect three-step skincare routine delivered to your door.
Is acne cream available over the counter?
Our acne cream is available by prescription only because it contains prescription-strength ingredients that you can’t get in even maximum strength OTC acne products. Prescription acne cream can effectively treat more severe forms of acne, like cystic acne. While there is no guarantee that any acne treatment will leave you acne-free, many women who were unable to effectively treat acne before find success with a prescription acne cream.

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