Provided by You Health for patients
Topiramate (Topamax®) + Vitamin B12 Tablets
Following consultation, a You Health provider determined that Topiramate + Vitamin B12 tablets are medically appropriate and necessary for your treatment. Topiramate + Vitamin B12 tablets are compounded products and are not FDA-approved. The FDA does not verify the safety or effectiveness of compounded drugs.
The following provides a medication overview of Topiramate + Vitamin B12, how the active ingredients work, and how to effectively and safely use it to support weight loss. You will also receive a medication guide with your medication, which contains full information about Topiramate + Vitamin B12. Please read all of the information before taking your medication.
Topiramate works by controlling appetite to reduce body fat . Topiramate is an FDA-approved medication for treating seizures and preventing migraines. It’s also commonly used off-label by leading obesity specialists and weight clinics to help with weight loss.
Vitamin B12 is a dietary supplement utilized in many areas of the body principally for the proper function of your red blood cells, nerve cells, energy levels and mood. Additionally it is used to supplement B12 when other drugs may possibly decrease its level.
UsageHow to get the most out of your treatment
Side EffectsWhat to look out for when using your treatment
WarningsImportant safety information
To get started, follow your provider's dosing instructions
You will begin treatment by slowly titrating up the dose of Topiramate + Vitamin B12 over a 4 or 5 week period, depending on the instructions given by your provider. Both schedules are shown in the tables below. Once you reach a dose of 1 tablet in the morning and 1 tablet in the evening you will remain at this dose unless instructed otherwise.
Missed a dose?
Take a missed dose as soon as you think about it. If it is less than 6 hours until the next dose, skip the missed dose and go back to the normal time. Do not take 2 doses at the same time or extra doses. If you miss 2 doses, contact your healthcare provider.
Do not abruptly stop taking Topiramate + Vitamin B12 or change your dose without talking with your healthcare provider first. Studies have shown that slowly decreasing your dose over time can reduce possible side-effects caused by stopping the medication abruptly.
4 Week Starter Plan (if instructed by your provider)
| Week | Morning | Evening |
|---|
| Week 1 | Take ½ tablet in the morning | _ |
| Week 2 | Take ½ tablet in the morning | Take ½ tablet in the evening |
| Week 3 | Take ½ tablet in the morning | Take 1 tablet in the evening |
| Week 4 | Take 1 tablet in the morning | Take 1 tablet in the evening |
5 Week Starter Plan (if instructed by your provider)
| Week | Morning | Evening |
|---|
| Week 1 | Take ½ tablet in the morning once every other day | _ |
| Week 2 | Take ½ tablet in the morning every day | _ |
| Week 3 | Take ½ tablet in the morning | Take ½ tablet in the evening |
| Week 4 | Take ½ tablet in the morning | Take 1 tablet in the evening |
| Week 4 | Take 1 tablet in the morning | Take 1 tablet in the evening |
Continue taking this medication as you have been instructed by your provider.
Even when taking Topiramate + Vitamin B12 or other antiepileptic medicines, some people with epilepsy will continue to have unpredictable seizures. Therefore, use caution and talk to your doctor before beginning any activities where loss of consciousness could result in serious danger to you or those around you (including swimming, driving a car, climbing in high places, etc.).
Message your healthcare provider right away if you have any of the symptoms above.
These are not the complete list of the side effects of Topiramate + Vitamin B12.
You can message a provider through your Hims & Hers account if you have any questions about your treatment, including any side effects you may be experiencing.
Tell your healthcare provider about any side effect that bothers you or that does not go away. You are encouraged to report all side effects to the FDA. Visit
www.fda.gov/medwatch, or call 1-800-FDA-1088.
Do not take Topiramate + Vitamin B12 if you:
These eye problems can lead to permanent loss of vision if not treated.
Should you notice any new eye symptoms, including any new problems with your vision, immediately discontinue use of Topiramate and seek urgent in-person evaluation. Please also message your provider team as soon as you are able.
Topiramate + Vitamin B12 may cause decreased sweating and increased body temperature (fever). People, especially children, should be watched for signs of decreased sweating and fever, especially in hot temperatures. Some people may need to be hospitalized for this condition. If a high fever, a fever that does not go away, or decreased sweating develops, call your healthcare provider right away.
Topiramate + Vitamin B12 can increase the level of acid in your blood (metabolic acidosis). If left untreated, metabolic acidosis can cause brittle or soft bones (osteoporosis, osteomalacia, osteopenia), kidney stones, can slow the rate of growth in children, and may possibly harm your baby if you are pregnant. Metabolic acidosis can happen with or without symptoms. Sometimes people with metabolic acidosis will:
While not a standard of care for healthcare providers who specialize in weight loss, a blood test to measure the level of acid in your blood before your treatment with Topiramate + Vitamin B12, can be considered. Should you wish to have this testing completed please inform a member of our care team. If you are pregnant, you should talk to your healthcare provider about whether you have metabolic acidosis.
Like other antiepileptic drugs, Topiramate + Vitamin B12 may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Message a healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you:
Topiramate + Vitamin B12 may lower bone mineral density. Topiramate + Vitamin B12 may decrease the density of bones when used over a long period.
Topiramate + Vitamin B12 may have negative effects on growth in children. Topiramate + Vitamin B12 may slow height increases and weight gain in children and adolescents when used over a long period
Do not stop Topiramate + Vitamin B12 without first talking to a healthcare provider.
How can I watch for early symptoms of suicidal thoughts and actions?
Topiramate + Vitamin B12 can harm your unborn baby.
Before taking Topiramate + Vitamin B12, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Topiramate + Vitamin B12 and other medicines may affect each other causing side effects. Especially tell your healthcare provider if you take:
Ask your healthcare provider if you are not sure if your medicine is listed above. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist each time you get a new medicine. Do not start a new medicine without talking with your healthcare provider.
If you no longer need your medication, the best way to dispose of most types of old, unused, unwanted, or expired medicines (both prescription and over the counter) is to drop off the medicine at a drug take back site, location, or program immediately. You can use the DEA DIVERSION CONTROL DIVISION LOOKUP to find your nearest drug disposal site.
If no drug take back sites, locations, or programs are available in your area, and there are no specific disposal instructions (such as flushing) in the medication guide or package insert, you can visit FDA- Disposal of Unused Medicines for more information or follow these simple steps to dispose of most medicines in your trash at home:
This is only a summary of the most important information about Topiramate + Vitamin B12.
Need more information?
Ask your healthcare provider or pharmacist.