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Start feeling like yourself again with access to clinically prescribed treatment plans to help ease symptoms.

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Not available in all 50 states. Prescription Required. Hormone replacement therapies are not FDA-approved for the treatment of perimenopause but may be prescribed off-label for perimenopausal symptoms at a provider’s discretion.

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Learn more about how to help relieve your symptoms with access to personalized treatment plans and 100% online care that works on your terms.

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Hormone replacement therapies are not FDA-approved for the treatment of perimenopause but may be prescribed off-label for perimenopausal symptoms at a provider’s discretion.

What treatment may look like

Get access to three parts for total support. After reviewing your intake, a provider will prescribe a combination that’s right for you if eligible.

Estradiol pill or patch

Progesterone pill

Estradiol vaginal cream

Perimenopause & Menopause by Hers includes hormonal health support, educational resources, and prescription options, if appropriate. Hormone replacement therapies are not FDA-approved for the treatment of perimenopause but may be prescribed off-label for perimenopausal symptoms at a provider’s discretion.


1. Based on separate randomized, placebo-controlled clinical trials of oral estradiol and estradiol patches in postmenopausal women that each found a reduction in hot flashes. Source.

2. Progesterone is for menopausal women with a uterus who are taking estrogen hormone replacement therapy. Progesterone helps protect the uterine lining. It is not independently approved for treating the symptoms of menopause. Source

3. In a meta-analysis of randomized clinical trials, oral micronized progesterone was shown to improve sleep quality in postmenopausal women by helping them fall asleep faster compared to placebo. Source.

4. In multiple randomized controlled trials, including a double-blind study of postmenopausal women, estradiol vaginal cream was shown to significantly improve vaginal dryness, itching, and irritation, and thinning of the vaginal lining. Source.

Plans created by experts, featuring you

Dr. Shepherd is a board certified OB/GYN, published author, and women’s health expert who has spent her career advocating for women’s health and education.

"You’re allowed to take up space, to take time, to ask again, to say you’re not okay. Having a good health team is what you deserve. You don’t have to ask for permission when you’re collaborating on your health.”

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  • 1

    Online intake

    Answer questions about what you’ve been experiencing and see which treatment options you may be eligible for.

  • 2

    Provider evaluation

    A licensed provider trained in women's health will review your intake and determine if treatment is right for you.

  • 3

    Personalized plan

    If prescribed, you’ll get a personalized treatment plan that includes medication delivered right to you.

  • 4

    Ongoing support

    Get unlimited online access to provider messaging, regular check-ins, and treatment adjustments as needed.

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Graph for illustrative purposes only. Individual hormone levels may vary.

Frequently asked questions

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What is perimenopause?

Perimenopause is the transitional phase leading up to menopause when hormone levels begin to fluctuate and decline and menstrual cycles become irregular.

When does perimenopause start?

Perimenopause often begins in your 40s but can start as early as the mid-30s. Every person’s timeline is different.

How long does perimenopause last?

On average, perimenopause lasts 4–6 years before menopause.

What are the first signs of perimenopause?

The earliest signs of perimenopause often include irregular periods, hot flashes, mood swings, sleep disruptions, and changes in menstrual flow.

What are the common symptoms of perimenopause?

Common symptoms of perimenopause include night sweats, brain fog, vaginal dryness, decreased fertility, and weight changes, in addition to irregular cycles.

Can you get pregnant during perimenopause?

Yes. Ovulation can still occur during perimenopause, even with irregular cycles, so pregnancy is still possible. Birth control may be needed until menopause is reached, so we encourage you to consult with your women’s health or primary care provider.

How do you test for perimenopause?

While there isn’t a single test to determine or diagnose perimenopause, certain lab tests may provide helpful insights. However, a healthcare provider should review your symptom severity and medical history to see if treatment is right for you.

Is spotting during perimenopause normal?

Light spotting during perimenopause, even just when wiping, can be common due to hormonal fluctuations. However, heavy bleeding or unusual patterns should always be checked by a provider.

Is weight gain a symptom of perimenopause?

Weight gain isn’t caused by perimenopause alone, but hormonal changes can shift fat storage, especially around the belly. Aging, metabolism, and lifestyle also play a role.

What is the difference between perimenopause and menopause?

Perimenopause is the lead-up to menopause. Menopause is a point in time that’s reached once you’ve gone 12 consecutive months without a period.

Is insurance required?

Insurance isn’t required, so there are no complicated insurance questions or health insurance plan considerations.

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